The Melanie Avalon Biohacking Podcast

#095 - Jonathan Bailor: Body Weight Setpoint, Burning Calories, Food Quality, Obesity & Diabetes Epidemic, Brain Inflammation, Hormonal Dysregulation & Gut Dysbiosis, The SANE Solution, And More!

May 28, 2021


1:55 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon

2:05 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!

2:30 - FOOD SENSE GUIDE: Get Melanie's App At To Tackle Your Food Sensitivities! Food Sense Includes A Searchable Catalogue Of 300+ Foods, Revealing Their Gluten, FODMAP, Lectin, Histamine, Amine, Glutamate, Oxalate, Salicylate, Sulfite, And Thiol Status. Food Sense Also Includes Compound Overviews, Reactions To Look For, Lists Of Foods High And Low In Them, The Ability To Create Your Own Personal Lists, And More!

3:00 - BEAUTYCOUNTER: Non-Toxic Beauty Products Tested For Heavy Metals, Which Support Skin Health And Look Amazing! Shop At For Something Magical! For Exclusive Offers And Discounts, And More On The Science Of Skincare, Get On Melanie's Private Beautycounter Email List At! Find Your Perfect Beautycounter Products With Melanie's Quiz: Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon At To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare!

6:40 - Jonathan's Personal History

11:35 - Why Do People Gain Or Lose Weight?

13:10 - The Global Economic Impact Of Diabetes

14:50 - What Happens With Calories That We Eat?

16:45 - The Calorie Is A Measure Of Energy Alone

18:00 - Why Does The Body Burn Or Store Calories?

19:50 - Dietary Induced Thermogenesis

20:00 - N.E.A.T. (Non-Exercise Activity Thermogenesis)

21:40 - DRY FARM WINES: Low Sugar, Low Alcohol, Toxin-Free, Mold- Free, Pesticide-Free, Hang-Over Free Natural Wine! Use The Link To Get A Bottle For A Penny!

23:20 - Perceived Rate Of Exertion

24:20 - Eat Less, Move Less

24:30 - What Is The Stress Response To A Crash Diet?

25:10 - Long Term Outcomes Of Crash Dieting

26:15 - Yo-Yo Dieting And The Extracellular Matrix

27:00 - Defining The "Set Point"

29:55 - How Do We Get Our Set Point? How Does It Change?

33:00 - Obesity As A Disease State 

34:00 - The Quality Of The Food We Eat

35:00 - The Overconsumption Of Food

36:40 - Hormone "Clogging"

39:35 - Parabiotic Studies

40:45 - The Communication Between Brain, Gut, And Hormones

43:40 - The Genetic Component

45:15 - LMNT: For Fasting Or Low-Carb Diets Electrolytes Are Key For Relieving Hunger, Cramps, Headaches, Tiredness, And Dizziness. With No Sugar, Artificial Ingredients, Coloring, And Only 2 Grams Of Carbs Per Packet. Try LMNT For Complete And Total Hydration. For A Limited Time Go To To Get  A FREE Sample Pack, Just Pay The Price Of Shipping!

47;55 - The Pervasive Shame In Being "Over-Fat" In Society

48:30 - SANESolution

50:25 - Evaluating Foods On A Spectrum For Optimal Health

52:10 - The SANE Food Groups

55:30 - What About Lower Fat Or Lower Carb?

57:05 - Metabolic Conditioning

59:10 - The Randall Cycle 

59:25 - The Myth Of Exercise

1:02:50 - Mechanical Removal Of Fat Cells

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